Table 3 Identification of the miRNAs analyzed in the validation phase and of the endogenous and exogenous miRNA normalizers. Each miRNA is identified by its NCBI accession number and sequence, according to miRBase v20. The pre-designed TaqMan Advanced miRNA Assays used to quantify the serum miRNA level are specified by their identification number (Applied Biosystems, Thermo Fisher Scientific)

hsa-miR-139-5p

MIMAT0000250

478312_mir

UCUACAGUGCACGUGUCUCCAGU

hsa-miR-200a-3p

MIMAT0000682

478490_mir

UAACACUGUCUGGUAACGAUGU

hsa-miR-1299

MIMAT0005887

478696_mir

UUCUGGAAUUCUGUGUGAGGGA

hsa-let-7e-5p

MIMAT0000066

478579_mir

UGAGGUAGGAGGUUGUAUAGUU

hsa-miR-16-5p

MIMAT0000069

477860_mir

UAGCAGCACGUAAAUAUUGGCG

hsa-miR-29a-3p

MIMAT0000086

478587_mir

UAGCACCAUCUGAAAUCGGUUA

hsa-miR-29b-3p

MIMAT0000100

478369_mir

UAGCACCAUUUGAAAUCAGUGUU

hsa-miR-29c-3p

MIMAT0000681

479229_mir

UAGCACCAUUUGAAAUCGGUUA

hsa-miR-93-5p

MIMAT0000093

478210_mir

CAAAGUGCUGUUCGUGCAGGUAG

hsa-miR-126-3p

MIMAT0000445

477887_mir

UCGUACCGUGAGUAAUAAUGCG

hsa-miR-132-3p

MIMAT0000426

477900_mir

UAACAGUCUACAGCCAUGGUCG

hsa-miR-146a-5p

MIMAT0000449

478399_mir

UGAGAACUGAAUUCCAUGGGUU

hsa-miR-184

MIMAT0000454

477938_mir

UGGACGGAGAACUGAUAAGGGU

hsa-miR-186-5p

MIMAT0000456

477940_mir

CAAAGAAUUCUCCUUUUGGGCU

hsa-miR-195-5p

MIMAT0000461

477957_mir

UAGCAGCACAGAAAUAUUGGC

hsa-miR-199a-5p

MIMAT0000231

478231_mir

CCCAGUGUUCAGACUACCUGUUC

hsa-miR-345-5p

MIMAT0000772

478366_mir

GCUGACUCCUAGUCCAGGGCUC

hsa-miR-375

MIMAT0000728

478074_mir

UUUGUUCGUUCGGCUCGCGUGA

hsa-miR-885-5p

MIMAT0004947

478207_mir

UCCAUUACACUACCCUGCCUCU

hsa-miR-191-5p

MIMAT0000440

477952_mir

CAACGGAAUCCCAAAAGCAGCUG

hsa-miR-222-3p

MIMAT0000279

477982_mir

AGCUACAUCUGGCUACUGGGU

hsa-miR-361-5p

MI0000760

481127_mir

UUAUCAGAAUCUCCAGGGGUAC

cel-miR-39-3p

MI0000010

478293_mir

UCACCGGGUGUAAAUCAGCUUG