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Table 5 Association analysis of rs30187 in samples positive and negative for HLA-B*27 and HLA-B*40. Odds ratios are given for the rs30187-risk A allele

From: MHC associations of ankylosing spondylitis in East Asians are complex and involve non-HLA-B27 HLA contributions

Group (case/control)

OR

P

All (1482/1512)

1.26

9.00 × 10−6

HLA-B27+ cases vs all controls (1323/1512)

1.29

2.71 × 10−6

HLA-B27− cases vs all controls (159/1512)

1.06

0.61

HLA-B27+ cases and controls (1323/77)

1.40

0.044

HLA-B27− cases and controls (159/1435)

1.06

0.64

HLA-B27+ cases vs HLA-B27− cases (1323/159)

1.21

0.11

HLA-B27+/HLA-B40+ (207/11)

1.25

0.60

HLA-B27+/HLA-B40− (1116/66)

1.42

0.050

HLA-B27−/HLA-B40− (89/1027)

1.11

0.49

HLA-B27−/HLA-B40+ (70/408)

1.02

0.91

  1. OR odds ratio in unconditional analysis, P P value in unconditional analysis, SE standard error of beta (log-odds) estimate, CHR chromosome
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Arthritis Research & Therapy

ISSN: 1478-6362

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