Fig. 3

The effects of macrophage reduction in the bleomycin-treated mice. a Representative skin sections from saline-, bleomycin-, saline plus clodronate-, or bleomycin plus clodronate-administered mice (hematoxylin and sirius red stain). Double head arrows indicate the dermal thickness. b The dermal thickness in the skin sections from mice (n = 4). c The expression of each protein in the skin from mice was examined by a Western blot analysis. The histogram shows quantitative representations of each protein (n = 3). d The skin sections of mice were stained with anti-α-SMA antibodies or anti-CD206 antibodies. The data represent the mean ± SEM. *P < 0.01, **P < 0.05