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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Alternatively activated macrophages are associated with the α2AP production that occurs with the development of dermal fibrosis

Fig. 5

The effects of IL-4Rα neutralization in the bleomycin-treated mice. a Representative skin sections from saline-, bleomycin plus control IgG-, or bleomycin plus IL-4Rα neutralizing antibodies-administered mice (hematoxylin and sirius red stain). Double head arrows indicate the dermal thickness. b The dermal thickness in the skin sections from mice (n = 4). c The expression of each protein in the skin from mice was examined by a Western blot analysis. The histogram shows quantitative representations of each protein (n = 3). d The skin sections of mice were stained with anti-α-SMA antibodies or anti-CD206 antibodies. The data represent the mean ± SEM. *P < 0.01. **P < 0.05

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