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Table 4 Multivariable logistic regression predicting high IFN score in JDM patients

From: Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies

Parameter

Estimate

Standard error

p value

Odds ratio

95% confidence interval

Lower

Upper

Constant

23.247

8.968

0.010

Total MMT score

− 0.099

0.037

0.007

0.91

0.84

0.97

LDH

− 0.013

0.007

0.073

0.99

0.97

1.00

Skeletal VAS

1.184

0.550

0.031

3.27

1.11

9.60

  1. High and low 28 interferon-regulated gene (IRG) score is defined by above and below 48.9, 95th percentile of healthy controls [22]. Backwards stepwise regression was performed (alpha < 0.15). p values < 0.05 are bolded. With the odds ratio, 1 is 1 point in the MMT score, LDH value, or 1 point on 10 point scale of skeletal VAS
  2. Abbreviations: Total MMT score 26 muscle manual muscle testing (0–260), LDH lactate dehydrogenase, skeletal VAS Myositis Disease Activity Assessment Tool Skeletal disease activity visual analog scale