Skip to main content
Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Higher interferon score and normal complement levels may identify a distinct clinical subset in children with systemic lupus erythematosus

Fig. 1

Interferon (IFN) signature analysis in thirty-one patients with childhood-onset systemic lupus erythematosus (cSLE) and ten healthy controls (CONTROLS). a Relative quantification (RQ) of interferon-stimulated genes (ISGs) (IFI27, IFI44L, IFIT1, ISG15, RSAD2, SIGLEC1) normalized on housekeeping genes. b IFN score calculated as the median of the RQ of the ISGs in patients and healthy controls. The dashed line represents the cut off value (2.466) determined by Crow [23, 36], to identify as positive/negative the IFN signature analysis. Results are reported as mean (shown in the figure) ± standard deviation. Data were analyzed with Mann-Whitney non-parametric test (****p < 0.0001)

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us