Fig. 4From: Sarilumab and adalimumab differential effects on bone remodelling and cardiovascular risk biomarkers, and predictions of treatment outcomesOdds ratios for achieving efficacy endpoints at week 24 by baseline biomarker tertile. Odds ratios (sarilumab vs. adalimumab) for achieving ACR20, ACR50 and DAS28-CRP < 3.2 responses at week 24 by baseline biomarker tertile. *Nominal biomarker-by-treatment interaction vs. low tertile. Low, medium and high subgroups are based on biomarker tertile values in overall treatment groups (see Table S3 for tertile ranges). ACR20/50, American College of Rheumatology 20/50% improvement criteria; CI, confidence interval; DAS28-CRP, Disease Activity Score (28 joints) using C-reactive protein; MMP-3, matrix metalloproteinase-3; NS, not significant at 5%; SAA, serum amyloid ABack to article page