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Table 5 National Paediatric Rheumatological Database (NPRD) with a uveitis add-on module in Germany (2002–2016). Initial uveitis documentation: anti-inflammatory treatment in previous 12 months. Data as provided in NPDR and/or uveitis documentation

From: Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany

Initial documentation.

Anti-inflammatory treatment in previous 12 months

Group I.

Uveitis, ANA-positive, no JIA, N = 62

Group II.

Uveitis manifestation after JIA disease onset*, N = 668

Group III.

Uveitis manifestation before JIA disease onset*, N = 61

p value†

Significant pairwise comparisons‡

 

Treatment

Uveitis inactivity‡‡

Treatment

Uveitis inactivity‡‡

Treatment

Uveitis inactivity‡‡

  

Any DMARD, n (%)

31 (52.5%)

2 (9.5%)

424 (65.6%)

63 (28.0%)

42 (70.0%)

1 (6.7%)

0.091

–

Methotrexate, n (%)

27 (45.8%)

1 (5.3%)

382 (59.1%)

59 (29.1%)

40 (66.7%)

1 (7.1%)

0.058

I vs. III

Adalimumab, n (%)

5 (8.5%)

1 (20.0%)

41 (6.4%)

8 (26.7%)

4 (6.7%)

0 (0.0%)

0.817

–

Systemic corticosteroids, n (%)

18 (29.0%)

1 (10.0%)

128 (19.3%)

22 (35.5%)

16 (26.2%)

1 (25.0%)

0.108

–

Topical corticosteroids, n (%)

36 (58.1%)

5 (19.2%)

388 (58.2%)

53 (23.5%)

37 (60.7%)

1 (8.3%)

0.930

–

  1. †Group effect for the proportion of treated patients by chi-squared test for categorical variables
  2. ‡Pairwise comparisons for the proportion of treated patients with correction for multiple comparisons by Bonferroni (chi-squared test)
  3. ‡‡Group I: n = 39; Group II: n = 355; Group III: n = 21 patients with documented AC cell count
  4. *Initial uveitis diagnosis