Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany

Table 6 National Paediatric Rheumatological Database (NPRD) with a uveitis add-on module in Germany (2002–2016). Uveitis characteristics at follow-up documentation. Data as provided in uveitis documentation

Follow-up documentation. Uveitis characteristics	Group I. Uveitis, ANA-positive, no JIA, N = 56			Group II. Uveitis manifestation after JIA disease onset*, N = 56			Group III. Uveitis manifestation before JIA disease onset*, N = 37			p value^†	Significant pairwise comparisons^‡
	N (%)	Mean	SD	N (%)	Mean	SD	N (%)	Mean	SD
Duration of uveitis onset until follow-up documentation, months	56	20.2	23.1	56	20.2	23.1	37	19.7	18.0	0.992	–
Unilateral uveitis, n (%), data provided in 110 cases	11 (27.5)	n.a.	n.a.	25 (61.0)	n.a.	n.a.	13 (44.8)	n.a.	n.a.	0.035	I vs. II
Bilateral uveitis, n (%), data provided in 110 cases	29 (72.5)	n.a.	n.a.	16 (39.0)	n.a.	n.a.	14 (55.2)	n.a.	n.a.
Inactive uveitis (AC cell grade < 0.5+); n (%), data provided in 74 cases	22 (64.7)	n.a.	n.a.	15 (55.8)	n.a.	n.a.	8 (61.5)	n.a.	n.a.	0.854	–
Visual acuity in uveitis eyes, logMAR	64	0.28	0.31	53	0.24	0.41	37	0.38	0.51	0.152	–
Worse eyes, logMAR	52	0.31	0.46	53	0.29	0.52	33	0.47	0.58	0.038	I vs. III, II vs. III

n.a. not applicable, n.s. not significant
*Initial uveitis diagnosis
^†Group effect for the proportion of treated patients by chi-squared test for categorical variables
^‡Pairwise comparisons for the proportion of treated patients with correction for multiple comparisons by Bonferroni (chi-squared test)

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