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Table 4 Disease incidence and maximum arthritis score with common mouse strains

From: Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis

Cocktail Mice B-LPS A-LPS
Incidence Max arthritis score (mean ± SEM) Incidence Max arthritis score (mean ± SEM)
2 mg Cab3 DBA/1 4/7 2.00 ± 0.95 7/7 22.86 ± 3.48
C57BL/6NQ 5/5 6.20 ± 1.50 5/5 28.40 ± 4.23*
BALB/c 1/7 1.43 ± 1.43 6/7 12.71 ± 4.98*
4 mg Cab3 BALB/c 2/7 1.29 ± 1.13 6/7 20.29 ± 6.26
  1. Comparisons were done in DBA/1, C57BL/6NQ, and Balb/c mice strains injected with 2 mg Cab3 in regard to max arthritis score. Significant difference was observed between C57BL/6NQ and Balb/c mice with 2 mg Cab3 after LPS injection. 2 mg Cab4 vs 2 mg anti-CII: *p < 0.05. The one-way ANOVA with Dunn’s multiple comparisons test was used to calculate the level of significance