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Table 3 Mean serum IL-16 levels based on organ or system involvement (frequency ≥ 25%) in AAV

From: Serum interleukin-16 significantly correlates with the Vasculitis Damage Index in antineutrophil cytoplasmic antibody-associated vasculitis

Involved organ system

Absence

Presence

P value

General

167.4 ± 188.5

124.2 ± 137.6

0.297

Ear, nose, and throat

112.3 ± 142.5

199.2 ± 194.5

0.030

Pulmonary

147.0 ± 130.3

155.4 ± 194.0

0.839

Renal

151.0 ± 151.9

153.8 ± 193.7

0.945

  1. Values are expressed as medians (interquartile ranges, IQR) or numbers (percentages)
  2. AAV ANCA-associated vasculitis, ANCA antineutrophil cytoplasmic antibody, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, BVAS Birmingham Vasculitis Activity Score, FFS Five-Factor Score, VDI Vasculitis Damage Index, SF-36 Short Form-36, P perinuclear, C cytoplasmic, MPO myeloperoxidase, PR-3 proteinase 3, AST aspartate aminotransferase, ALT alanine aminotransferase, ESR erythrocyte sedimentation rate, CRP C-reactive protein