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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

Fig. 5

Regulation of Th17/Treg cells in obese mice with CIA by rapamycin–metformin treatment. a Rapamycin–metformin decreased the frequency of Th17 cells within the CD4+ T cell population and induced Treg production in the spleen tissues of obese mice with CIA. Original magnification, × 400. Tissues were analyzed from five mice of each group. Data represent the mean ± SD. *P < 0.05

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