Fig. 5From: Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndromeRegulation of Th17/Treg cells in obese mice with CIA by rapamycin–metformin treatment. a Rapamycin–metformin decreased the frequency of Th17 cells within the CD4+ T cell population and induced Treg production in the spleen tissues of obese mice with CIA. Original magnification, × 400. Tissues were analyzed from five mice of each group. Data represent the mean ± SD. *P < 0.05Back to article page