Table 4 Risk for heart failure, myocardial infarction, and stroke hospitalization and all-cause mortality among Medicare beneficiaries

 Events/person-years

19,407/3,064,851

1477/115,128

–

 Incidence rate (95% CI)*

6.3 (6.2, 6.4)

12.8 (12.2, 13.5)

–

  Model 1

1 (reference)

1.72 (1.63, 1.82)

< 0.001

  Model 2

1 (reference)

1.74 (1.65, 1.83)

< 0.001

  Model 3

1 (reference)

1.32 (1.25, 1.39)

< 0.001

 Events/person-years

27,553/3,039,727

1479/114,759

–

 Incidence rate (95% CI)*

9.1 (9.0, 9.2)

12.9 (12.2, 13.5)

–

  Model 1

1 (reference)

1.19 (1.13, 1.26)

< 0.001

  Model 2

1 (reference)

1.21 (1.15, 1.27)

< 0.001

  Model 3

1 (reference)

1.06 (1.00, 1.11)

0.05

 Events/person-years

22,657/3,050,349

1152/115,356

–

 Incidence rate (95% CI)*

7.4 (7.3, 7.5)

10.0 (9.4, 10.6)

–

  Model 1

1 (reference)

1.14 (1.07, 1.21)

< 0.001

  Model 2

1 (reference)

1.14 (1.08, 1.22)

< 0.001

  Model 3

1 (reference)

1.06 (1.00, 1.12)

0.07

 Events/person-years

145,623/3,101,396

7013/117,902

–

 Incidence rate (95% CI)*

47.0 (46.7, 47.2)

59.5 (58.1, 60.9)

–

  Model 1

1 (reference)

1.02 (1.00, 1.05)

0.08

  Model 2

1 (reference)

1.04 (1.02, 1.07)

0.001

  Model 3

1 (reference)

0.95 (0.93, 0.98)

< 0.001