Fig. 3

Methylation status at the TSDR of the foxp3 gene in CD4⁺Foxp3⁺ T cells in active SLE patients and healthy controls. a A representative dot plot of the target cell populations sorted using a FACS Vantage flow cytometer: CD4⁺Foxp3⁺ cells and CD4⁺Foxp3⁻ cells. b The mean proportion of demethylated TSDRs in isolated CD4⁺Foxp3⁺ cells and CD4⁺Foxp3⁻ cells in healthy controls (n = 6) and active SLE patients (n = 6)