Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

Table 3 Diagnostic performance of FOI measuring synovitis using MRI and GS synovitis as reference

FOI	FOI+/MRI+	FOI−/MRI-	Sens.	Spec.	PPV	NPV	AUC	PA
PVM	698/1456	1180/1635	0.48	0.72	0.61	0.61	0.61	61
Phase 1	22/1442	1621/1635	0.02	0.99	0.61	0.53	0.50	53
Phase 2	814/1408	984/1585	0.58	0.62	0.58	0.62	0.60	60
Phase 3	332/1407	1408/1572	0.24	0.90	0.67	0.57	0.57	58
FOI	FOI+/GS+	FOI−/GS−	Sens.	Spec.	PPV	NPV	AUC	PA
PVM	407/688	3510/5473	0.59	0.64	0.17	0.93	0.62	64
Phase 1	16/680	5412/5454	0.02	0.99	0.28	0.89	0.51	88
Phase 2	461/667	2977/5299	0.69	0.56	0.17	0.94	0.63	58
Phase 3	152/664	4545/5273	0.23	0.86	0.17	0.90	0.56	79

FOI fluorescence optical imaging, PVM FOI Prima Vista Mode, Phase 1 FOI phase 1, Phase 2 FOI phase 2, Phase 3 FOI phase 3, MRI magnetic resonance imaging, GS gray-scale ultrasound, Sens. sensitivity, Spec. specificity, PPV positive predictive value, NPV negative predictive value, PA percent agreement, AUC area under the curve

ISSN: 1478-6362