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Table 3 Diagnostic performance of FOI measuring synovitis using MRI and GS synovitis as reference

From: Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

FOI FOI+/MRI+ FOI−/MRI- Sens. Spec. PPV NPV AUC PA
PVM 698/1456 1180/1635 0.48 0.72 0.61 0.61 0.61 61
Phase 1 22/1442 1621/1635 0.02 0.99 0.61 0.53 0.50 53
Phase 2 814/1408 984/1585 0.58 0.62 0.58 0.62 0.60 60
Phase 3 332/1407 1408/1572 0.24 0.90 0.67 0.57 0.57 58
FOI FOI+/GS+ FOI−/GS− Sens. Spec. PPV NPV AUC PA
PVM 407/688 3510/5473 0.59 0.64 0.17 0.93 0.62 64
Phase 1 16/680 5412/5454 0.02 0.99 0.28 0.89 0.51 88
Phase 2 461/667 2977/5299 0.69 0.56 0.17 0.94 0.63 58
Phase 3 152/664 4545/5273 0.23 0.86 0.17 0.90 0.56 79
  1. FOI fluorescence optical imaging, PVM FOI Prima Vista Mode, Phase 1 FOI phase 1, Phase 2 FOI phase 2, Phase 3 FOI phase 3, MRI magnetic resonance imaging, GS gray-scale ultrasound, Sens. sensitivity, Spec. specificity, PPV positive predictive value, NPV negative predictive value, PA percent agreement, AUC area under the curve