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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Fig. 2

Autoantibody data in anti-CCP2-positive RA, anti-CCP2-negative RA, and controls. a Prevalence of IgM, IgG, and IgA RF. b Median IgM, IgG, and IgA RF levels among RF-positive individuals; asterisks (*) indicate significantly lower IgM, IgG, and IgA RF levels in controls compared to RA patients (p < 0.0001 for all). c Co-occurrence of different RF isotypes among RF-positive individuals, in anti-CCP2-positive RA (n = 1655/1766), anti-CCP2-negative RA (n = 298/989), and controls (n = 39/370). d Prevalence of different autoantibody groups (ACPA, RF, and other autoantibodies). Co-occurrence of different autoantibody groups among autoantibody-positive individuals, in anti-CCP2-positive RA (n = 1753/1766), anti-CCP2-negative RA (n = 591/989), and controls (n = 137/370)

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