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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Asiatic acid attenuates hypertrophic and fibrotic differentiation of articular chondrocytes via AMPK/PI3K/AKT signaling pathway

Fig. 7

Effects of AA on chondrocyte hypertrophy in rats. a–c Immunohistochemistry analysis of and MMP13, COL-X, and Runx2 in sections of tibial plateau of knee joints. d Quantitative data of percentage of MMP13-, COL-X-, and Runx2-positive cells in each group (n = 3 for each group). One-way ANOVA, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Boxed regions in the bottom panels are shown in the top panels

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