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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Increased serum calpain activity is associated with HMGB1 levels in systemic sclerosis

Fig. 1

Expression of calpain-related genes in patients with SSc or SSc-ILD. a Differentially expressed heatmap of calpain-associated genes in lung samples of patients with SSc-ILD (GSE40839, GSE48149, GSE76808, GSE81292). b Differentially expressed heatmap of calpain-associated genes in PBMC samples of patients with SSc (GSE33463). c Differentially expressed heatmap of calpain-associated genes in skin samples of patients with SSc (GSE58095). d Differentially expressed boxplot of calpain-associated genes in lung samples of patients with SSc-ILD (50 SSc-ILD vs 28 HC). e Differentially expressed boxplot of calpain-associated genes in PBMC samples of patients with SSc (69 SSc vs 41 HC). f Differentially expressed boxplot of calpain-associated genes in skin samples of patients with SSc (59 SSc vs 43 HC). *p < 0.05, **p < 0.01, ***p < 0.001. Abbreviations: SSc systemic sclerosis, ILD interstitial lung disease, HC healthy control subjects

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