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Table 3 Laboratory parameters of IgG4-RD patients with/without PAO/PA

From: IgG4-related aortitis/periaortitis and periarteritis: a distinct spectrum of IgG4-related disease

ParametersPAO/PA (n = 89)Non-PAO/PA (n = 498)P value
HgB (g/L)127 ± 21135 ± 19< 0.001*
WBC (109/L)7.9 ± 2.87.15 ± 2.550.014*
PLT (109/L)240 ± 87238 ± 890.862
Eos% elevation (%)22.532.40.077
ESR (mm/h), M (Q1–Q3)44 (18–75)16 (7–40)< 0.0001*
Elevation of ESR (n, %)61 (77.1%, 61/70)205 (42.0%, 205/488)< 0.001*
hsCRP (mg/L), M (Q1–Q3)6.72 (2.14–24.65)1.78 (0.72–5.12)< 0.0001*
Elevation of hsCRP (n, %)56 (70%, 56/80)150 (37.5%, 150/400)< 0.001*
IgG (g/L)19.88 ± 8.2021.28 ± 14.460.292
IgA (g/L)2.53 ± 1.132.16 ± 1.290.02*
IgM (g/L), M (Q1–Q3)0.88 (0.56–1.14)0.77 (0.54–1.19)0.573
IgG1 (mg/L), M (Q1–Q3)9355 (7928–11,325)8665 (7013–10,600)0.03
IgG2 (mg/L), M (Q1–Q3)5705 (4255–7350)5595 (4290–7520)0.873
IgG3 (mg/L), M (Q1–Q3)461 (221–923)439 (253–841)0.802
IgG4 (mg/L), M (Q1–Q3)4240 (2015–7730)8310 (3250–17,075)< 0.0001*
T-IgE (KU/L), M (Q1–Q3)170 (95.3–463.5)332 (119–720.5)0.025*
Cr (μmol/L)98.5 (73–131.3)67 (57.7–78)< 0.0001*
Elevation of Cr (n, %)38 (50)14 (2.8)< 0.001*
C3 (g/L)1.018 ± 0.3220.948 ± 0.3300.725
C4 (g/L)0.217 ± 0.1120.173 ± 0.1020.004*
  1. M (Q1–Q3) represented median (quartile 1to quartile 3)
  2. *Statistical significance