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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Fig. 3

Relationship between circulating TL1A and disease duration, serological markers, and clinical activity in RA. a Plasma TL1A measured in the indicated groups of subjects from the SERA cohort. FDR: first-degree relatives grouped into those with or without anti-CCP antibodies. ERA, early RA (< 1 year); CRA, chronic RA (> 1 year). Significance of differences given by Mann-Whitney test with Bonferroni correction for multiple testing. Serum TL1A in RA patients from the SNUH cohort grouped by RF positivity (b) and anti-CCP positivity (c). Significance of the difference given by Mann-Whitney test. *p ≤ 0.05, **p ≤ 0.01,***p ≤ 0.001, ****p ≤ 0.0001. d Linear correlation of serum TL1A and DAS28 CRP in the SNUH RA cohort

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