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Table 1 The demographic, clinical, and laboratory characteristics of patients with AOSD and sepsis

From: Interleukin-18 and fibroblast growth factor 2 in combination is a useful diagnostic biomarker to distinguish adult-onset Still’s disease from sepsis

Characteristic

AOSD patients (n = 70)

Sepsis patients (n = 22)

Healthy controls (n = 118)

p value (AOSD vs. sepsis)

Age at diagnosis, years

48 (33–65)

59 (44–71)

56 (47–65)

0.12

Female, n (%)

44 (71)

12 (54)

11 (58)

0.17

Ferritin at diagnosis, ng/mL

4019 (1184–11,870)

   

CRP at diagnosis, mg/L

87 (48–135)

116 (99–148)

 

0.056

ESR at diagnosis, mm/h

48 (34–73)

   

WBC at diagnosis, /μL

12,290 (6690–17,455)

15,300 (13,625–18,500)

 

0.12

AST at diagnosis, U/L

50 (31–93)

   

ALT at diagnosis, U/L

36 (17–112)

   

SOFA score

 

3 (2.8–4.3)

  

DIC, n (%)

3 (4)

3 (17)

 

0.26

MAS, n (%)

5 (7)

0 (0)

  
  1. CRP C-reactive protein, ESR erythrocyte sedimentation rate, WBC white blood cell, AST aspartate aminotransferase, ALT alanine animotransferase, SOFA Sequential Organ Failure Assessment, DIC disseminated intravascular coagulation, MAS macrophage activation syndrome