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Table 4 Long-term stability of HCQ in whole blood. HCQ concentrations in three WB samples stored up to 168 h (1 week) at either in RT or in the refrigerator (4 °C)

From: Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS—evaluation of whole blood, plasma, and serum as sample matrices

 Patient 1Patient 2Patient 3
HoursRT, ng/mLRefrigerator, ng/mLRT, ng/mLRefrigerator, ng/mLRT, ng/mLRefrigerator, ng/mL
0770432307
8778776403416304295
24777755421411293307
48754848410397284303
72784760429391325295
168 (1 week)756780449410291305
Mean ± SD (ng/mL)770 ± 13781 ± 34424 ± 17409 ± 14301 ± 15302 ± 6
CV%1.64.33.93.54.91.9