Table 4 Long-term stability of HCQ in whole blood. HCQ concentrations in three WB samples stored up to 168 h (1 week) at either in RT or in the refrigerator (4 °C)
| Patient 1 | Patient 2 | Patient 3 | ||||
|---|---|---|---|---|---|---|
| Hours | RT, ng/mL | Refrigerator, ng/mL | RT, ng/mL | Refrigerator, ng/mL | RT, ng/mL | Refrigerator, ng/mL |
| 0 | 770 | 432 | 307 | |||
| 8 | 778 | 776 | 403 | 416 | 304 | 295 |
| 24 | 777 | 755 | 421 | 411 | 293 | 307 |
| 48 | 754 | 848 | 410 | 397 | 284 | 303 |
| 72 | 784 | 760 | 429 | 391 | 325 | 295 |
| 168 (1 week) | 756 | 780 | 449 | 410 | 291 | 305 |
| Mean ± SD (ng/mL) | 770 ± 13 | 781 ± 34 | 424 ± 17 | 409 ± 14 | 301 ± 15 | 302 ± 6 |
| CV% | 1.6 | 4.3 | 3.9 | 3.5 | 4.9 | 1.9 |