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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice

Fig. 5

SOX9 immunostaining shows a decrease in positive cells in Mig-6-overexpressing mice at p0 and 6 weeks. Immunostaining of SOX9 in the knee joints of control (a/e) and Mig-6over/over (Mig-6over/overCol2a1-Cre+/−) (b/f) mice. Total cell number/area from control and Mig-6over/over mice (c/g). Percentage of Sox9-positive cells from control and Mig-6over/over at p0 and 6 weeks (d/h). Data analyzed by two-tailed Student t tests from 5 mice per group. Individual data points presented with mean ± SEM (P < 0.05). Scale bar = 100 μm and 50 μm

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