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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice

Fig. 6

Lubricin immunostaining is slightly decreased in the articular cartilage of cartilage-specific Mig-6-overexpressing mice at 11 weeks of age. Immunostaining of sections of the knee joint indicates the presence of lubricin (PRG4) in superficial zone chondrocytes. IHC reveals no staining for the negative control (c). Sections from Mig-6 KO mice served as the positive control (d). N = 4–5 mice/genotyping. Scale bar = 100 μm

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