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Table 1 Baseline characteristics of the study population

From: Interleukin-32 in systemic sclerosis, a potential new biomarker for pulmonary arterial hypertension

 

SSc-PAH

SSc

Idiopathic PAH

Healthy control

N

18

21

15

14

Men/woman (Nof patients)

2/16

3/18

5/10

3/11

Disease duration (years ± SD

21.1 ± 7.6

19.1 ± 9.0

20.0 ± 10

 

Age (mean, years ± SD)

69.8 ± 8.0

60.5 ± 9.3

62.5 ± 14.6

63.7 ± 10.1

lcSSc/dcSSc (Nof patients)

5/13

7/14

  

ACA/Scl70 (Nof patients)

5/13

7/14

  

Digital ulcers (Nof patients)

2

1

  

sPAP eco

73.1 ± 16.6

23.3 ± 4.4

68.7 ± 20.5

 

mPAP RHC

43.0 ± 10.6

 

49.9 ± 21.0

 

mRSS in dcSSc (mean ± SD)

16.8 ± 2.4

10.6 ± 7.1

  

mRSS in lcSSc (mean ± SD)

3.6 ± 2.5

3.9 ± 2.3

  

Prostanoid

Not

Not

Not

Not

Calcium-channel blockers

Not

Not

Not

Not

Phosphodiestererase-5 inhibitors

Not

Not

Not

Not

Endothelin-1 receptors antagonists

Not

Not

Not

Not

Vasoactive therapies

Not

Not

Not

Not

  1. ACA anti-centromere antibodies, dcSSc diffuse cutaneous SSc, lcSSc limited cutaneous SSc, mPAP RHC mean pulmonary artery pressure measured by RHC, mRSS modified Rodnan skin score, N number, PAH Pulmonary arterial hypertension, RHC right heart catheterization, SD standard deviation, sPAP eco systolic pulmonary artery pressure measured by echocardiography, SSc systemic sclerosis