TY - JOUR AU - Abrar, Daniel B. AU - Schleich, Christoph AU - Nebelung, Sven AU - Frenken, Miriam AU - Ullrich, Tim AU - Radke, Karl Ludger AU - Antoch, Gerald AU - Vordenbäumen, Stefan AU - Brinks, Ralph AU - Schneider, Matthias AU - Ostendorf, Benedikt AU - Sewerin, Philipp PY - 2020 DA - 2020/05/29 TI - Proteoglycan loss in the articular cartilage is associated with severity of joint inflammation in psoriatic arthritis—a compositional magnetic resonance imaging study JO - Arthritis Research & Therapy SP - 124 VL - 22 IS - 1 AB - Even though cartilage loss is a known feature of psoriatic arthritis (PsA), little is known about its role in the pathogenesis of PsA. Using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) as a non-invasive marker of the tissue’s proteoglycan content, such early (i.e., pre-morphological) changes have been associated with inflammation in rheumatoid arthritis (RA). Yet, this association has not been studied before in PsA. SN - 1478-6362 UR - https://doi.org/10.1186/s13075-020-02219-7 DO - 10.1186/s13075-020-02219-7 ID - Abrar2020 ER -