Fig. 1From: Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus diseaseDependence of cGVHD-associated autoimmunity on CD4+ T cell Ezh2. bm12 mice (5 mice/group) were injected ip with 1 × 107 negatively selected CD4+ T cells from C57BL/6 (WT) or B6.CD4.Ezh2-KO (Ezh2) mice. Mouse sera were collected weekly. Total IgG and autoantibodies against dsDNA and chromatin were analyzed by ELISA [16, 19]. Data are representative of four repeats. Error bars show standard deviations. Student’s t test, *p < 0.05; **p < 0.01Back to article page