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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: TNF-α inhibitor therapy can improve the immune imbalance of CD4+ T cells and negative regulatory cells but not CD8+ T cells in ankylosing spondylitis

Fig. 1

Cluster analyses of immunophenotypic parameters. Each column represents individual AS patient or HC, and the color code in the first line above the graph indicates AS group (red) or HC group (green). The rows represent immune cells that are differentially expressed in AS and HC with a P value < 0.05. The magnitude of parameter expression is color-coded with red for a relative increase in expression and blue for a relative decrease in expression. CM CD4+T cell, central memory CD4+T cell; EM CD4+T cell, effector memory CD4+T cell; CM CD8+T cell, central memory CD8+T cell; EM CD8+T cell, effector memory CD8+T cell; Th cell, helper T cell; Tfh cell, follicular helper T cell; Tc cell, cytotoxic T lymphocyte; Treg cell, regulatory T cell; Breg cell, regulatory B cell

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