Variables | Crude IRR (CI95%) | p | Adjusted IRR (CI95%) | p |
---|---|---|---|---|
Age (ref. adult)* | ||||
Young | 0.76 (0.54–1.09) | 0.140 | 1.00 (0.66–1.53) | 0.985 |
Elderly | 1.61 (1.36–1.91) | < 0.001 | 1.42 (1.13–1.77) | 0.002 |
Very elderly | 2.01 (1.45–2.79) | < 0.001 | 1.89 (1.27–2.81) | 0.002 |
Female gender | 1.33 (1.20–1.49) | < 0.001 | 1.43 (1.23–1.66) | < 0.001 |
Diagnosis (ref. RA) | ||||
AS | 0.80 (0.70–0.91) | 0.001 | 1.10 (0.91–1.33) | 0.336 |
PsA | 0.96 (0.84–1.09) | 0.512 | 1.12 (0.94–1.33) | 0.208 |
Comorbidities | ||||
Charlson Index | 1.15 (1.09–1.22) | < 0.001 | 1.14 (1.07–1.22) | < 0.001 |
Smoking (ref. No) | ||||
Smoker/past smoker | 1.25 (1.11–1.41) | < 0.001 | 1.31 (1.12–1.52) | 0.001 |
Treatments | ||||
Corticosteroids (ref. No) | 1.31 (1.17–1.46) | < 0.001 | 1.1 (0.96–1.26) | 0.192 |
Initial mean dose corticosteroids | 1.00 (0.99–1.01) | 0.842 | 0.99 (0.97–1.00) | 0.100 |
MTX (ref. No) | 1.41 (1.26–1.58) | < 0.001 | 1.40 (1.22–1.61) | < 0.001 |
Other DMARDs (ref. No) | 1.17 (1.05–1.31) | 0.006 | 1.29 (1.12–1.50) | 0.001 |
Time of disease duration& | 1.01 (1.00–1.01) | 0.054 | 1.14 (1.07–1.22) | < 0.001 |