Table 3 IRR of time to first AE stratified by diagnostic group. Poisson regression model, crude, and adjusted

1.16 (0.62–2.17)

0.639

1.20 (0.62–2.33)

0.585

0.47 (0.19–1.13)

0.091

0.49 (0.18–1.31)

0.153

0.85 (0.52–1.39)

0.53

1.13 (0.67–1.90)

0.65

1.59 (1.30–1.95)

< 0.001

1.55 (1.23–1.95)

< 0.001

1.60 (1.08–2.36)

0.019

1.25 (0.89–1.97)

0.336

1.36 (0.73–2.56)

0.336

1.34 (0.63–2.86)

0.446

1.77 (1.24–2.52)

0.002

1.76 (1.18–2.61)

0.005

4.35 (1.40–13.57)

0.011

4.40 (1.30–14.87)

0.017

5.94 (1.48–23.84)

0.012

2.86 (0.65–12.59)

0.165

1.00 (0.83–1.20)

0.99

1.14 (0.93–1.41)

0.209

1.72 (1.40–2.11)

< 0.001

1.60 (1.26–2.04)

< 0.001

1.35 (1.07–1.70)

0.012

1.42 (1.09–1.85)

0.01

1.01 (0.86–1.18)

0.913

1.73 (1.37–2.18)

< 0.001

1.48 (1.13–1.93)

0.004

1.59 (1.17–2.16)

0.003

1.35 (0.95–1.91)

0.098

1.26 (1.07–1.47)

0.004

1.25 (1.07–1.47)

0.006

1.34 (1.07–1.69)

0.012

1.31 (1.01–1.68)

0.041

1.78 (1.36–2.31)

< 0.001

1.56 (1.13–2.14)

0.006

1.08 (0.93–1.25)

0.325

1.37 (1.09–1.72)

0.008

1.43 (1.09–1.88)

0.01

1.02 (0.76–1.36)

0.897

1.29 (1.09–1.53)

0.004

1.28 (1.05–1.57)

0.015

1.36 (1.07–1.73)

0.012

1.09 (0.81–1.46)

0.578

1.26 (1.01–1.58)

0.042

1.18 (0.90–1.54)

0.234

1.12 (1.05–1.20)

0.001

1.08 (1.00–1.17)

0.048

1.13 (1.00–1.29)

0.056

1.09 (0.93–1.29)

0.293

1.26 (1.07–1.47)

0.005

1.28 (1.06–1.54)

0.01

1.00 (0.99–1.01)

0.818

1.01 (0.99–1.03)

0.399

1.01 (1.00–1.03)

0.008

1.02 (1.01–1.03)

0.004