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Table 3 Reasons for discontinuation of bDMARDs in non-adjusted data

From: Differential long-term retention of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis by age group from the FIRST registry

N

< 65 yr

65–74 yr

≥75 yr

TNFi

ABA

TCZ

TNFi

ABA

TCZ

TNFi

ABA

TCZ

456

123

116

229

114

59

121

115

29

Remission

77 (16.9)

9 (7.3)

4 (3.4)

24 (10.5)

4 (3.5)

3 (5.1)

12 (9.9)

4 (3.5)

1 (3.4)

Effect insufficiency

66 (14.5)

27 (22.0)

18 (15.5)

53 (23.1)

23 (20.2)

5 (8.5)

22 (18.2)

22 (19.1)

5 (17.2)

Adverse events

43 (9.4)

6 (4.9)

10 (8.6)

29 (12.7)

12 (10.5)

8 (13.6)

22 (18.2)

5 (4.3)

2 (6.9)

Others

44 (9.6)

8 (6.5)

2 (1.7)

15 (6.6)

3 (2.6)

1 (1.7)

4 (3.3)

5 (4.3)

1 (3.4)

  1. Values are the number (%)
  2. yr years, TNFi tumor necrosis factor inhibitors, ABA abatacept, TCZ tocilizumab