Table 1 Demographic data, clinical and laboratory parameters of human subjects involved in the study
From: Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis
Parameter | Lupus nephritis | SLE without nephritis | Healthy controls |
|---|---|---|---|
Sum | 16 | 18 | 24 |
Gender | Female | Female | Female |
Age: Mean (SD) [range] years | 33 (6.5) [24–42] | 39 (8.7) [20–50] | 28 (7.1) [21–50] |
Race/ethnicity | |||
Caucasian | 12 (75%) | 18 (100%) | 24 (100%) |
Asian | 1 (6.2%) | 0 (0%) | 0 (0%) |
Other races | 3 (18.7%) | 0 (0%) | 0 (0%) |
NR | 1 (6.2%) | 0 (0%) | 0 (0%) |
Pyuria (WBC/μl) [Mean (SD), range] | 41.4 (58.3) [10–166] | – | – |
Proteinuria (g/L) [Mean (SD), range] | 1.52 (1.2) [0.05–3.58] | – | – |
Urinary creatinine (mg/dL) [Mean, (SD) range] | 123.9 (66.2) [51–262] | – | – |
GFR [Mean, (SD) range] | 94.1 (41.5) [29–168] | – | – |
C3 (mg/L) [Mean (SD), range] | 0.77 (0.2) [0.5–1.25] | – | – |
CRP (mg/L) [Mean (SD), range] | 9 (10.9) [< 1–28] | – | – |
Serum creatinine (mg/dL) [Mean (SD), range] | 0.85 (0.4) [0.45–1.94] | – | – |
Serum albumin (g/L) [Mean (SD), range] | 22 (17.8) [3.3–44.1] | – | – |
SLEDAI | 8.7 (5.8) [0–21] | – | – |
LN class | |||
II/III | 1 (6.2%) | – | – |
III | 2 (12.5%) | – | – |
III/ IV | 2 (12.5%) | – | – |
IV | 8 (50%) | – | – |
V | 1 (6.2%) | – | – |
NR | 2 (12.5%) | – | – |
Flare status | – | ||
YES | 5 (31.3%) | 2 (11.1%) | – |
NO | 11 (68.7%) | 16 (88.9%) | – |
Medication | |||
Corticosteroids | 15 (93.7%) | 13 (72.2%) | – |
Immunosuppressant | 14 (87.5%) | 10 (55.6%) | – |
Anti-malarial | 15 (93.7%) | 17 (94.4%) | – |