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Table 1 Demographic data, clinical and laboratory parameters of human subjects involved in the study

From: Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis

Parameter Lupus nephritis SLE without nephritis Healthy controls
Sum 16 18 24
Gender Female Female Female
Age: Mean (SD) [range] years 33 (6.5) [24–42] 39 (8.7) [20–50] 28 (7.1) [21–50]
Race/ethnicity
 Caucasian 12 (75%) 18 (100%) 24 (100%)
 Asian 1 (6.2%) 0 (0%) 0 (0%)
 Other races 3 (18.7%) 0 (0%) 0 (0%)
 NR 1 (6.2%) 0 (0%) 0 (0%)
Pyuria (WBC/μl) [Mean (SD), range] 41.4 (58.3) [10–166]
Proteinuria (g/L) [Mean (SD), range] 1.52 (1.2) [0.05–3.58]
Urinary creatinine (mg/dL) [Mean, (SD) range] 123.9 (66.2) [51–262]
GFR [Mean, (SD) range] 94.1 (41.5) [29–168]
C3 (mg/L) [Mean (SD), range] 0.77 (0.2) [0.5–1.25]
CRP (mg/L) [Mean (SD), range] 9 (10.9) [< 1–28]
Serum creatinine (mg/dL) [Mean (SD), range] 0.85 (0.4) [0.45–1.94]
Serum albumin (g/L) [Mean (SD), range] 22 (17.8) [3.3–44.1]
SLEDAI 8.7 (5.8) [0–21]
LN class
 II/III 1 (6.2%)
 III 2 (12.5%)
 III/ IV 2 (12.5%)
 IV 8 (50%)
 V 1 (6.2%)
 NR 2 (12.5%)
Flare status   
 YES 5 (31.3%) 2 (11.1%)
 NO 11 (68.7%) 16 (88.9%)
Medication
 Corticosteroids 15 (93.7%) 13 (72.2%)
 Immunosuppressant 14 (87.5%) 10 (55.6%)
 Anti-malarial 15 (93.7%) 17 (94.4%)
  1. NR not reported, GFR glomerular filtration rate, C3 complement component 3, CRP C-reactive protein, WBC white blood cells, SLEDAI SLE disease activity index