Skip to main content

Table 2 Histopathology evaluation of kidneys from Sle123 discovery set

From: Proteomic analysis in lupus mice identifies Coronin-1A as a potential biomarker for lupus nephritis

Animals Glomerulus Tubules
Hypercell/PMN/cell debris Thrombi/fibrosis Interstitial inflammation Tubular involvement/atrophy
12 weeks
1 0 0 0 0
2 0 0 0 0
3 0 0 0 0
4 0 0 0 0
5 0 0 0 0
Mean 0 0 0 0
24 weeks
1 3 1 1 1
2 1 0 0 0
3 1 0 1 0
4 3 1 3 1
5 0 0 1 2
Mean 1.6 0.4 1.2 0.8
36 weeks
1 2 3 3 1
2 1 0 0 0
3 1 0 1 0
4 1 0 0 0
5 3 0 3 2
Mean 1.6 0.6 1.4 0.6
  1. Grading: 0 = normal, 1 = mild, 2 = moderate, 3 = severe. PMN Polymorphonuclear neutrophils