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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: An integrative Bayesian network approach to highlight key drivers in systemic lupus erythematosus

Fig. 3

The alterations in SLE signaling pathway based on calculated final parameters. The representation design of KEGG-extracted SLE signaling pathways (a), genes involved in autoantigen clearance (b), antigen presentation mediated by MHCII (c), and tissue injury and end-organ damage (d). The color and size of nodes reflect the values and the absolute values of the μ(βf), respectively, and it is equivalent to the upregulation or downregulation of genes. Moreover, the color of the edges reflects the values of the μ(βf), respectively, and it is equivalent to the increasing or decreasing biological function

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