Fig. 5

Male PRΔPrx1-CIA mice had higher amounts of surface osteoclasts at the distal femoral subchondral bone. (a) Representative TRAP-stained knee histologic images from female or (b) male in WT or PRΔPrx1 normal or CIA mice. (c) Quantitative measurements of TRAP+ surface osteoclasts at the distal femoral subchondral bone. Black arrows illustrate TRAP+ cells at bone surfaces. *p < 0.05 between indicated groups. Scale bar = 100 μm