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Table 4 Univariate and multivariate Cox-regression analysis for the predictors of total hip arthroplasty in patients with subchondral insufficient fracture of the femoral head

From: Predictors of cartilage degeneration in patients with subchondral insufficiency fracture of the femoral head: a retrospective study

Variables

Univariate analysis

Multivariate analysis

 

P value

HR

95% CI

P value

HR

95% CI

Sex

0.493

1.56

0.438–5.557

   

Age

0.020

1.07

1.011–1.129

   

BMI

0.659

0.98

0.889–1.077

   

Osteoporosis therapy

0.665

0.72

0.161–3.208

   

Period from onset to diagnosis

0.021

1.28

1.038–1.578

   

Weight-bearing limitation

0.107

0.35

0.099–1.251

0.727

0.77

0.179–3.324

MRI findings

 Band length

< 0.001

1.30

1.152–1.455

0.001

1.29

1.116–1.495

 Band over the edge of AC

0.014

3.87

1.317–11.375

0.042

3.66

1.049–12.803

 Intensity change of AC

0.001

28.85

3.677–226.286

0.007

29.15

2.517–337.594

Bone metabolic marker

 P1NP, μg/ml

0.018

1.013

1.002–1.024

0.148

1.01

0.997–1.023

 TRACP 5b, mU/dL

0.007

1.005

1.001–1.008

0.114

1.00

0.999–1.008

  1. Multivariate analyses were adjusted for sex, age, BMI, anti-osteoporosis therapy, and period from pain onset
  2. HR hazard ratio, CI confidence interval, BMI body mass index, AC acetabulum, P1NP intact type 1 procollagen-N-propeptide, TRACP 5b: tartrate-resistant acid phosphatase 5b