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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren’s syndrome

Fig. 1

Gene expression profile of B cell subsets in patients with pSS and HCs. a Study protocol. b Hierarchical clustering analysis and c principal component analysis to summarize the dissimilarity of the transcriptome of each B cell subset. Rows correspond to genes and columns to samples. The ellipse shows the 50% confidence interval of the value of principal component analysis. d Dysregulated genes are shown in the volcano plot. Horizontal green lines show the cut-off of the p value indicating a significant difference, and the vertical green lines show a log2-fold change. DEG, differentially expressed gene; GC-B, germinal centre B cell: HC, healthy control; pSS, primary Sjögren’s syndrome; WGCNA, weighted gene co-expression network analysis

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Arthritis Research & Therapy

ISSN: 1478-6362

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