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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren’s syndrome

Fig. 5

Gene network characteristics and hub genes in the gene networks of B cells of pSS. a Hierarchical clustering analysis with a heatmap of enriched pathways (left), upstream regulators (middle) and disease/functions (right). b Top five significantly enriched canonical pathways (left), upstream regulators (middle) and disease and biological functions (right) in the modules of pSS. The colour of each frame corresponds to a module colour. c Associations of intra- and inter-modular hub genes in patients with pSS. Node colour corresponds to module colour. The pink-coded edge represents the correlation, and the green-coded edge represents an inverse correlation. The width of the edge reflects the absolute weight of a correlation

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Arthritis Research & Therapy

ISSN: 1478-6362

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