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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Elevated expression of BAFF receptor, BR3, on monocytes correlates with B cell activation and clinical features of patients with primary Sjögren’s syndrome

Fig. 5

Suppressive effect of anti-IL-6 receptor antibody on IgG production by B cells co-cultured with monocytes. Monocytes and B cells from pSS patients (n = 4) were cultured as described in the legend of Fig. 4. Anti-IL-6 receptor antibody or isotype control antibody was added into the culture at day 0, and the culture supernatants were harvested on day 4. The amount of IgG produced by the cells in the supernatants was measured by ELISA, and the IgG level was normalized against levels in “B + mono”. *p < 0.05, **p < 0.01

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