Fig. 1
From: Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase
Gene and protein expression and tyrosine phosphatase activity in WT and Shp1-Tg samples. aShp1 gene expression was determined by RT-qPCR from spleen samples of 8–12-week-old female mice of each genotype. b Tyrosine phosphatase activity was measured in spleen samples of mice after SHP-1 immunoprecipitation. c SHP-1 protein expression was detected by Western blot in the spleen and bone marrow samples (mean ± SEM in panel a, % of WT in Fig. 1b, n = 3–7 mice/group, *p < 0.05, **p < 0.01, ***p < 0.001; ****p < 0.0001; one-way ANOVA)