Fig. 3
From: Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase
PGIA incidence and severity in WT, Shp1-Tg+/+, and Shp1-Tg+/− mice. Mice were immunized 4 times with human PG then monitored and scored for symptoms of arthritis. a Arthritis incidence is expressed as the percent of arthritic mice of all immunized animals in each group. b Area under the curve (AUC) of arthritis incidence. c Arthritis severity is expressed as the mean visual arthritis score ± SEM. d AUC of arthritis severity (n = 10/group, ****p < 0.0001, WT vs the other groups; ANOVA followed by Dunn’s multiple comparison). AUCs are shown as box plots (center line, median; box limits, upper and lower quartiles; whiskers, maximu, and minimum values)