Fig. 7
From: Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase
Net cytokine secretion in regorafenib treated WT or Shp1-Tg+/− PGIA mice. a IFNγ, b IL-17, c IL-10, and d IL-4. Spleen cells of PGIA mice were stimulated with PG in vitro for 4 days then secreted cytokines were measured in the cell culture supernatants. Net cytokine secretion (pg/ml) is illustrated as stimulated minus non-stimulated values (mean ± SEM, n = 5/group, one-way ANOVA)