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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

Fig. 1

Comparison of AHA levels between HC and RA patients. AHA1, AHA2, AHA3, and AHA4 represent IgG AHA against TCZ IgG1 F(ab’)2pepsin, TCZ IgG1 F(ab’)2MMP-3, NTZ IgG4 F(ab’)2pepsin, and NTZ IgG4 F(ab’)2MMP-3, respectively. AHA5, AHA6, AHA7, and AHA8 represent IgA AHAs against TCZ IgG1 F(ab’)2pepsin, TCZ IgG1 F(ab’)2MMP-3, NTZ IgG4 F(ab’)2pepsin, and NTZ IgG4 F(ab’)2MMP-3, respectively. Differences in levels between HC and RA were analyzed with the Mann-Whitney U test

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Arthritis Research & Therapy

ISSN: 1478-6362

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