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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

Fig. 2

Comparison of AHA levels in RA stratified by the presence or absence of RF and anti-CCP2 antibodies (CCP). Double positive RA (DPRA) indicates RA patients being positive for both RF and CCP. Double negative RA (DNRA) indicates RA patients being neither. Single positive RA (SPRA) indicates RA patients being either positive for RF [SPRA (RF)] or positive for CCP [SPRA (CCP)]. The number of patients in each RA group is shown. The non-parametric Kruskal-Wallis test was used to compare the 4 groups

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