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Table 1 Characteristics of patients with RA and healthy controls (HC)

From: IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

 

RA (n = 111)

HC (n = 81)

P

Age, years*

63.0 (53.3–66.0)

57.0 (49.8–64.0)

0.004

Women, n (%)

91 (82.0)

60 (74.1)

0.21

Duration of disease, years*

5.0 (3.0–12.0)

  

bDMARDs, n (%)

77 (69.4)

  

CDAI*

3.4 (1.4–8.3)

  

HAQ score*

0.13 (0–0.75)

  

Steinbrocker’s stage, n (%)

 I

18 (16.2)

  

 II

35 (31.5)

  

 III

15 (13.5)

  

 IV

43 (38.7)

  

Smoking, n (%)

34 (30.6)

NA

 

Autoantibodies, n (%)

 RF (+)/RF (−)

67 (60.4)/44 (39.6)

NA

 

Anti-CCP2 (+)/anti-CCP2 (−)/NA

77 (69.4)/28 (25.2)/6 (5.4)

NA

 
  1. NA not available. *Values are the median (interquartile range) unless otherwise indicated. Among bDMARDs, tocilizumab was administered in 30 patients