Skip to main content

Table 3 Univariate and multivariate logistic regression analyses of the association between AHA and RA

From: IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

Variable

Univariate analysis

Multivariate analysis

OR (95% CI)

P

OR (95% CI)

P

Analysis 1: total RA vs. HC

 Age

1.03 (0.99–1.06)

0.075

1.04 (1.00–1.09)

0.037

 Gender

1.59 (0.79–3.17)

0.189

2.19 (0.86–5.62)

0.100

 AHA1

1.01 (1.00–1.01)

0.001

1.00 (0.99–1.00)

0.992

 AHA2

1.00 (0.99–1.00)

0.295

–

–

 AHA3

1.18 (1.09–1.27)

1 × 10−5

1.16 (1.07–1.26)

3 × 10−4

 AHA4

1.03 (1.00–1.06)

0.025

1.00 (0.96–1.04)

0.825

 AHA5

1.03 (1.02–1.05)

8 × 10−5

1.02 (1.00–1.03)

0.034

 AHA6

1.06 (1.03–1.09)

4 × 10−4

1.01 (0.98–1.04)

0.367

 AHA7

1.16 (1.05–1.28)

0.004

1.04 (0.96–1.13)

0.339

 AHA8

1.65 (1.30–2.09)

3 × 10−4

1.20 (0.89–1.62)

0.226

Analysis 2: DNRA vs. HC

 Age

1.04 (0.98–1.11)

0.226

1.07 (0.98–1.15)

0.115

 Gender

2.62 (0.59–13.21)

0.193

9.29 (1.01–85.3)

0.049

 AHA1

0.99 (0.99–1.01)

0.898

–

–

 AHA2

1.00 (0.99–1.00)

0.243

–

–

 AHA3

1.16 (1.06–1.27)

0.002

1.18 (1.06–1.32)

0.003

 AHA4

1.03 (0.99–1.07)

0.112

1.03 (0.98–1.08)

0.311

 AHA5

1.01 (0.99–1.03)

0.062

1.01 (0.99–1.03)

0.186

 AHA6

1.00 (0.98–1.03)

0.664

–

–

 AHA7

1.06 (0.98–1.15)

0.143

–

–

 AHA8

1.21 (0.83–1.70)

0.347

–

–

  1. The number of RA patients in analysis 1 and in analysis 2 was 106 and 18, respectively. The number of HC was same as 81 in both analyses
Back to article page