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Table 4 Univariate and multivariate logistic regression analyses of the association between AHA and RA when patients with non-RA were used as a subject

From: IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

Variable

Univariate analysis

Multivariate analysis

OR (95% CI)

P

OR (95% CI)

P

Age

1.01 (0.98–1.03)

0.62

1.00 (0.97–1.03)

0.89

Gender

0.78 (0.32–1.91)

0.58

0.57 (0.21–1.54)

0.27

AHA1

1.00 (0.99–1.01)

0.22

1.00 (0.99–1.00)

0.90

AHA3

1.08 (1.03–1.12)

3.3 × 10−4

1.08 (1.03–1.13)

9.9 × 10−4

AHA5

1.01 (0.99–1.01)

0.10

1.00 (0.99–1.02)

0.41

AHA7

1.05 (0.98–1.12)

0.15

0.98 (0.90–1.08)

0.73

  1. The numbers of patients with RA and non-RA were 59 and 61, respectively. All of non-RA patients including six patients with Sjogren’s syndrome (3 primary and 6 secondary) did not show persistent destructive polyarthritis, namely RA-like symptom or sign
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