Table 3 Reconstitution of peripheral blood cells in percentages and absolute cell numbers per μl after aHSCT

Before aHSCT

Month 1

Month 3

Month 6

Month 12

Before aHSCT

Month 1

Month 3

Month 6

Month 12

Leucocytes

na

na

na

na

na

9.8 (IQR 8.4–13.6)

10.7 (8.3–12.2)

7.6 (5.4–10.5)

7.1 (6.4–8.5)^†

7.1 (5.8–9.1)^†

Neutrophils

77.5 (67.8–83.5)

75.0 (70.5–82.0)

77.0 (69.8–86.3)

79.0 (65.5–82.0)

71.5 (62.0–79.3)

8.5 (6.1–10.8)

7.9 (5.9–9.7)

6.0 (4.3–8.0)

5.6 (4.3–6.4)^†

5.2 (3.7–7.1)^†

Lymphocytes

11.5 (7.3–18.0)

9.5 (5.3–14.8)

10.0 (6.8–17.3)

12.0 (6.5–22.0)

15.5 (11.0–21.0)

1.1 (0.8–1.9)

1.0 (0.6–1.4)

0.7 (0.5–1.0)^†

0.9 (0.5–1.6)^†

1.2 (0.5–1.5)

Monocytes

8.5 (5.3–10.8)

9.0 (6.3–13.0)

10.0 (5.0–13.3)

9.0 (7.5–12.0)

8.5 (7.3–10.0)

0.9 (0.5–1.1)

1.0 (0.6–1.4)^†

0.6 (0.5–0.9)

0.6 (0.4–1.0)^†

0.6 (0.5–0.9)^†

T cells CD3⁺

72.0 (58.5–78.8)

51.5 (23.0–63.3)^†

37.0 (33.0–55.5)^†

46.0 (32.4–68.0)^†

60.0 (37.5–62.5)^†

745.5 (462.0–1593.7)

473.1 (150.5–837.6)

257.4 (187.5–433.4)^†

325.7 (165.7–796.2)^†

539.4 (237.2–775.6)^†

T helper cells CD3⁺/CD4⁺

50.0 (37.0–57.0)

8.5 (4.3–11.8)^†

7.0 (4.5–10.8)^†

11.0 (5.3–17.3)^†

20.0 (15.0–26.5)^†

605.9 (325.6–829.0)

78.3 (36.7–160.7)^†

49.2 (28.4–95.2)^†

109.4 (26.7–202.1)^†

201.6 (75.8–396.9)^†

Cytotoxic T cells CD3⁺/CD8⁺

14.0 (9.2–21.0)

39.0 (22.0–49.3)^†

28.5 (19.3–34.3)^†

20.5 (15.5–51.8)^†

32.0 (19.5–44.5)^†

146.3 (82.2–286.2)

335.7 (112.8–736.0)

174.8 (115.8–289.4)

140.9 (119.9–543.2)

228.3 (147.1–515.2)

CD4⁺/CD8⁺ ratio

3.4 (1.8–5.2)

0.3 (0.2–0.4)^†

0.3 (0.2–0.4)^†

0.3 (0.2–0.9)^†

0.5 (0.4–1.1)^†

na

na

na

na

na

NK cells CD56/CD16⁺

17.0 (6.0–20.0)

43.5 (25.5–55.8)^†

33.5 (22.8–44.3)^†

24.0 (17.3–36.0)^†

18.0 (10.0–35.5)^†

193.6 (103.4–247.5)

325.4 (240.8–534.9) ^†

205.2 (149.5–346.5)

196.9 (134.3–309.1)

216.1 (123.1–283.0)

NKT cells CD3⁺/CD56/CD16⁺

1.8 (1.0–3.2)

2.0 (0.4–3.2)

2.1 (0.2–3.2)

1.1 (0.4–3.4)

1.6 (1.0–2.2)

28.6 (10.3–50.8)

12.8 (4.6–33.7)

13.6 (3.5–23.6)

8.8 (4.8–32.1)^†

11.7 (5.8–26.6)

Total B cells CD19⁺

5.9 (4.9–15.0)

1.2 (0.3–3.4)^†

13.5 (1.4–29.0)

22.0 (3.8–32.5)^†

24.0 (11.9–31.3)^†

83.2 (47.8–136.7)

7.9 (1.4–50.1)^†

138.9 (10.4–238.1)

215.0 (20.8–291.3)

291.0 (148.9–379.4)^†

Transitional B cells CD38⁺⁺/CD10⁺/IgD⁺

1.0 (0.3–6.7)

55.0 (7.5–81.8)^†

17.7 (13.4–50.4)^†

5.8 (3.5–19.3)^†

6.2 (1.6–16.1)^†

1.1 (0.2–15.7)

4.2 (0.1–12.5)

28.2 (3.4–47.7)^†

9.7 (2.0–92.1)^†

10.7 (5.5–49.6)^†

Double negative B cells CD27⁻/IgD⁻

3.1 (2.5–6.4)

3.9 (2.0–16.1)

0.8 (0.5–1.8)^†

1.4 (0.6–2.2)^†

1.6 (1.4–2.5)^†

3.6 (1.5–8.4)

1.2 (0.1–1.7)^†

1.2 (0.6–2.3)^†

2.0 (0.9–4.6)

5.8 (3.4–8.8)

Post-switched memory B cells CD27⁺/IgD⁻

9.2 (4.1–18.3)

8.4 (0.9–55.3)

0.9 (0.5–1.9)^†

1.7 (0.5–5.0)^†

2.6 (1.1–2.9)^†

6.6 (4.3–13.1)

0.6 (0.2–1.0)^†

1.3 (0.4–2.2)^†

2.7 (0.6–5.2)^†

5.8 (3.1–10.7)

Pre-switched memory B cells CD27⁺/IgD⁺

6.4 (3.0–10.8)

4.0 (2.3–7.5)

2.5 (1.7–6.3)

2.9 (2.1–4.1)^†

2.1 (1.8–4.2)^†

4.5 (1.8–10.8)

0.2 (0.1–1.7)^†

4.4 (0.9–6.0)^†

4.6 (1.1–11.0)

7.2 (4.4–11.3)

Naïve B cells CD27⁻/IgD⁺

77.0 (60.0–87.2)

76.6 (5.7–92.9)

95.3 (88.4–96.4)

93.8 (89.5–96.2)^†

92.4 (91.2–96.2)^†

58.9 (32.4–130.5)

6.1 (1.2–38.1)^†

127.4 (28.3–238.0)

212.1 (44.1–285.2)^†

293.0 (180.8–353.2)^†