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Table 4 Analyses based on different inheritance models on the FBN2 locus

From: Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population

Locus SNPs Model Genotypes or alleles SLE n Control n OR 95% CI p
FBN2 Codominant GG 21 26 1.75 0.93–3.27 7.96E−02
rs74989671 Dominant AG 235 334 1.53 1.25–1.86 2.38E−05
AA 562 1219 ref ref ref
AG+GG 256 360 1.54 1.27–1.87 8.83E−06
AA 562 1219 ref ref ref
Recessive GG 21 26 1.57 0.84–2.93 0.161
AG + AA 797 1553 ref ref ref
Allelic A 277 386 ref ref ref
G 1359 2772 1.38 1.17–1.64 1.31E−04
FBN2 Codominant GG 655 1366 0.72 0.23–2.47 5.80E−01
rs76835745 Dominant AG 162 212 1.15 0.36–4 1.00
AA 6 9 ref ref ref
GG+GA 817 1578 0.78 0.25–2.66 0.60
AA 6 9 ref ref ref
Recessive GG 655 1366 0.63 0.5–0.79 5.43E−05
AA+GA 168 221 ref ref ref
Allelic A 174 230 ref ref ref
G 1472 2944 12.34 10.6–14.4 2.20E−16