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Table 4 Analyses based on different inheritance models on the FBN2 locus

From: Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population

Locus SNPs

Model

Genotypes or alleles

SLE n

Control n

OR

95% CI

p

FBN2

Codominant

GG

21

26

1.75

0.93–3.27

7.96E−02

rs74989671

Dominant

AG

235

334

1.53

1.25–1.86

2.38E−05

AA

562

1219

ref

ref

ref

AG+GG

256

360

1.54

1.27–1.87

8.83E−06

AA

562

1219

ref

ref

ref

Recessive

GG

21

26

1.57

0.84–2.93

0.161

AG + AA

797

1553

ref

ref

ref

Allelic

A

277

386

ref

ref

ref

G

1359

2772

1.38

1.17–1.64

1.31E−04

FBN2

Codominant

GG

655

1366

0.72

0.23–2.47

5.80E−01

rs76835745

Dominant

AG

162

212

1.15

0.36–4

1.00

AA

6

9

ref

ref

ref

GG+GA

817

1578

0.78

0.25–2.66

0.60

AA

6

9

ref

ref

ref

Recessive

GG

655

1366

0.63

0.5–0.79

5.43E−05

AA+GA

168

221

ref

ref

ref

Allelic

A

174

230

ref

ref

ref

G

1472

2944

12.34

10.6–14.4

2.20E−16