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Table 2 Ranked Gene Ontology (GO) terms significantly affected by dexamethasone

From: Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq

GO term

Description

FDR p-value

GO:0048523

Negative regulation of cellular process

3.50E-08

GO:0032502

Developmental process

3.81E-08

GO:0048519

Negative regulation of biological process

4.05E-08

GO:0030334

Regulation of cell migration

5.17E-08

GO:0051239

Regulation of multicellular organismal process

1.69E-07

GO:0032501

Multicellular organismal process

4.37E-07

GO:0007166

Cell surface receptor signaling pathway

4.66E-07

GO:0043062

Extracellular structure organization

6.75E-06

GO:0030198

Extracellular matrix organization

7.34E-06

GO:0048856

Anatomical structure development

7.86E-06

GO:0032879

Regulation of localization

7.91E-06

GO:0009725

Response to hormone

1.25E-05

GO:0042127

Regulation of cell proliferation

1.27E-05

GO:0050896

Response to stimulus

3.12E-05

GO:0040011

Locomotion

0.000137

GO:0048518

Positive regulation of biological process

0.000193

GO:0050794

Regulation of cellular process

0.000197

GO:0040008

Regulation of growth

0.000199

GO:0048583

Regulation of response to stimulus

0.000351

GO:0065008

Regulation of biological quality

0.000584

GO:0043408

Regulation of MAPK cascade

0.00105

GO:0009719

Response to endogenous stimulus

0.00152

GO:0006954

Inflammatory response

0.00235

GO:0006950

Response to stress

0.00241

GO:0065007

Biological regulation

0.00281

GO:0051174

Regulation of phosphorus metabolic process

0.00303

GO:0010273

Detoxification of copper ion

0.00306

GO:0048878

Chemical homeostasis

0.0032

GO:0010941

Regulation of cell death

0.00426

GO:0070482

Response to oxygen levels

0.00506

GO:0061687

Detoxification of inorganic compound

0.0057

GO:0006928

Movement of cell or subcellular component

0.00578

GO:0022610

Biological adhesion

0.00626

GO:0009611

Response to wounding

0.0064

GO:0007155

Cell adhesion

0.00717

GO:0065009

Regulation of molecular function

0.0116

GO:0051338

Regulation of transferase activity

0.023

GO:0006068

Ethanol catabolic process

0.0239

GO:0019216

Regulation of lipid metabolic process

0.0255

GO:0009628

Response to abiotic stimulus

0.0342

GO:0006109

Regulation of carbohydrate metabolic process

0.0375

GO:0051246

Regulation of protein metabolic process

0.039

GO:0002682

Regulation of immune system process

0.0425

GO:0032964

Collagen biosynthetic process

0.0429

GO:0008283

Cell proliferation

0.0454

  1. FDR p-value = False discovery rate -corrected p-value