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Table 2 Ranked Gene Ontology (GO) terms significantly affected by dexamethasone

From: Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq

GO term Description FDR p-value
GO:0048523 Negative regulation of cellular process 3.50E-08
GO:0032502 Developmental process 3.81E-08
GO:0048519 Negative regulation of biological process 4.05E-08
GO:0030334 Regulation of cell migration 5.17E-08
GO:0051239 Regulation of multicellular organismal process 1.69E-07
GO:0032501 Multicellular organismal process 4.37E-07
GO:0007166 Cell surface receptor signaling pathway 4.66E-07
GO:0043062 Extracellular structure organization 6.75E-06
GO:0030198 Extracellular matrix organization 7.34E-06
GO:0048856 Anatomical structure development 7.86E-06
GO:0032879 Regulation of localization 7.91E-06
GO:0009725 Response to hormone 1.25E-05
GO:0042127 Regulation of cell proliferation 1.27E-05
GO:0050896 Response to stimulus 3.12E-05
GO:0040011 Locomotion 0.000137
GO:0048518 Positive regulation of biological process 0.000193
GO:0050794 Regulation of cellular process 0.000197
GO:0040008 Regulation of growth 0.000199
GO:0048583 Regulation of response to stimulus 0.000351
GO:0065008 Regulation of biological quality 0.000584
GO:0043408 Regulation of MAPK cascade 0.00105
GO:0009719 Response to endogenous stimulus 0.00152
GO:0006954 Inflammatory response 0.00235
GO:0006950 Response to stress 0.00241
GO:0065007 Biological regulation 0.00281
GO:0051174 Regulation of phosphorus metabolic process 0.00303
GO:0010273 Detoxification of copper ion 0.00306
GO:0048878 Chemical homeostasis 0.0032
GO:0010941 Regulation of cell death 0.00426
GO:0070482 Response to oxygen levels 0.00506
GO:0061687 Detoxification of inorganic compound 0.0057
GO:0006928 Movement of cell or subcellular component 0.00578
GO:0022610 Biological adhesion 0.00626
GO:0009611 Response to wounding 0.0064
GO:0007155 Cell adhesion 0.00717
GO:0065009 Regulation of molecular function 0.0116
GO:0051338 Regulation of transferase activity 0.023
GO:0006068 Ethanol catabolic process 0.0239
GO:0019216 Regulation of lipid metabolic process 0.0255
GO:0009628 Response to abiotic stimulus 0.0342
GO:0006109 Regulation of carbohydrate metabolic process 0.0375
GO:0051246 Regulation of protein metabolic process 0.039
GO:0002682 Regulation of immune system process 0.0425
GO:0032964 Collagen biosynthetic process 0.0429
GO:0008283 Cell proliferation 0.0454
  1. FDR p-value = False discovery rate -corrected p-value